Do apicomplexan parasites hijack the host cell microRNA pathway for their intracellular development?

RNA silencing plays an important role in development through the action of microRNAs, which fine tune the expression of a large portion of the genome. It is also very important in innate immune responses, especially in antiviral and antibacterial defenses in plants, insects, and animals. Two recent...

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Detalles Bibliográficos
Autores principales: Hakimi, Mohamed-Ali, Ménard, Robert
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950041/
https://www.ncbi.nlm.nih.gov/pubmed/20948791
http://dx.doi.org/10.3410/B2-42
Descripción
Sumario:RNA silencing plays an important role in development through the action of microRNAs, which fine tune the expression of a large portion of the genome. It is also very important in innate immune responses, especially in antiviral and antibacterial defenses in plants, insects, and animals. Two recent papers now indicate that apicomplexan parasites display the ability to interfere with host microRNA populations.

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