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DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO
Insulin/IGF-1 signaling controls metabolism, stress resistance and aging in Caenorhabditis elegans by regulating the activity of the DAF-16/FoxO transcription factor (TF). However, the function of DAF-16 and the topology of the transcriptional network that it crowns remain unclear. Using chromatin p...
Autores principales: | Schuster, Eugene, McElwee, Joshua J, Tullet, Jennifer M A, Doonan, Ryan, Matthijssens, Filip, Reece-Hoyes, John S, Hope, Ian A, Vanfleteren, Jacques R, Thornton, Janet M, Gems, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950082/ https://www.ncbi.nlm.nih.gov/pubmed/20706209 http://dx.doi.org/10.1038/msb.2010.54 |
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