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The DNA/RNA-Dependent RNA Polymerase QDE-1 Generates Aberrant RNA and dsRNA for RNAi in a Process Requiring Replication Protein A and a DNA Helicase
The production of aberrant RNA (aRNA) is the initial step in several RNAi pathways. How aRNA is produced and specifically recognized by RNA-dependent RNA polymerases (RdRPs) to generate double-stranded RNA (dsRNA) is not clear. We previously showed that in the filamentous fungus Neurospora, the RdRP...
Autores principales: | Lee, Heng-Chi, Aalto, Antti P., Yang, Qiuying, Chang, Shwu-Shin, Huang, Guocun, Fisher, Daniel, Cha, Joonseok, Poranen, Minna M., Bamford, Dennis H., Liu, Yi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950127/ https://www.ncbi.nlm.nih.gov/pubmed/20957187 http://dx.doi.org/10.1371/journal.pbio.1000496 |
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