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Protein Evolution by Molecular Tinkering: Diversification of the Nuclear Receptor Superfamily from a Ligand-Dependent Ancestor
Understanding how protein structures and functions have diversified is a central goal in molecular evolution. Surveys of very divergent proteins from model organisms, however, are often insufficient to determine the features of ancestral proteins and to reveal the evolutionary events that yielded ex...
Autores principales: | Bridgham, Jamie T., Eick, Geeta N., Larroux, Claire, Deshpande, Kirti, Harms, Michael J., Gauthier, Marie E. A., Ortlund, Eric A., Degnan, Bernard M., Thornton, Joseph W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950128/ https://www.ncbi.nlm.nih.gov/pubmed/20957188 http://dx.doi.org/10.1371/journal.pbio.1000497 |
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