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Interactions between Exposure to Environmental Polycyclic Aromatic Hydrocarbons and DNA Repair Gene Polymorphisms on Bulky DNA Adducts in Human Sperm

BACKGROUND: Nucleotide excision repair (NER) and base excision repair (BER) are the primary mechanisms for repair of bulky adducts caused by chemical agents, such as PAHs. It is expected that polymorphisms in NER or BER genes may modulate individual susceptibility to PAHs exposure. Here, we evaluate...

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Detalles Bibliográficos
Autores principales: Ji, Guixiang, Gu, Aihua, Zhou, Yong, Shi, Xiangguo, Xia, Yankai, Long, Yan, Song, Ling, Wang, Shoulin, Wang, Xinru
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950145/
https://www.ncbi.nlm.nih.gov/pubmed/20957144
http://dx.doi.org/10.1371/journal.pone.0013145