Complex comprised of dextran magnetite and conjugated cisplatin exhibiting selective hyperthermic and controlled-release potential

We developed a dextran-magnetite conjugated cisplatin (DM-Cis) complex for use in thermal ablation and as a chemotherapeutic drug. To produce DM-Cis we reacted Cis with 1 mL DM (56 mg/mL iron). The temperature rise of DM-Cis was measured in vitro and in vivo under a portable induction-heating (IH) d...

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Detalles Bibliográficos
Autores principales: Sonoda, Akinaga, Nitta, Norihisa, Nitta-Seko, Ayumi, Ohta, Shinich, Takamatsu, Shigeyuki, Ikehata, Yoshio, Nagano, Isamu, Jo, Jun-ichiro, Tabata, Yasuhiko, Takahashi, Masashi, Matsui, Osamu, Murata, Kiyoshi
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950408/
https://www.ncbi.nlm.nih.gov/pubmed/20957172

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