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Suboptimal Porcine Endogenous Retrovirus Infection in Non-Human Primate Cells: Implication for Preclinical Xenotransplantation

BACKGROUND: Porcine endogenous retrovirus (PERV) poses a potential risk of zoonotic infection in xenotransplantation. Preclinical transplantation trials using non-human primates (NHP) as recipients of porcine xenografts present the opportunity to assess the zoonosis risk in vivo. However, PERV poorl...

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Detalles Bibliográficos
Autores principales: Mattiuzzo, Giada, Takeuchi, Yasuhiro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950858/
https://www.ncbi.nlm.nih.gov/pubmed/20949092
http://dx.doi.org/10.1371/journal.pone.0013203