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Characterization of LINE-1 Ribonucleoprotein Particles
The average human genome contains a small cohort of active L1 retrotransposons that encode two proteins (ORF1p and ORF2p) required for their mobility (i.e., retrotransposition). Prior studies demonstrated that human ORF1p, L1 RNA, and an ORF2p-encoded reverse transcriptase activity are present in ri...
Autores principales: | Doucet, Aurélien J., Hulme, Amy E., Sahinovic, Elodie, Kulpa, Deanna A., Moldovan, John B., Kopera, Huira C., Athanikar, Jyoti N., Hasnaoui, Manel, Bucheton, Alain, Moran, John V., Gilbert, Nicolas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951350/ https://www.ncbi.nlm.nih.gov/pubmed/20949108 http://dx.doi.org/10.1371/journal.pgen.1001150 |
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