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Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis
Transforming growth factor-beta (TGF-β), a multifunctional cytokine regulating several immunologic processes, is expressed by virtually all cells as a biologically inactive molecule termed latent TGF-β (LTGF-β). We have previously shown that TGF-β activity increases during influenza virus infection...
Autores principales: | Carlson, Christina M., Turpin, Elizabeth A., Moser, Lindsey A., O'Brien, Kevin B., Cline, Troy D., Jones, Jeremy C., Tumpey, Terrence M., Katz, Jacqueline M., Kelley, Laura A., Gauldie, Jack, Schultz-Cherry, Stacey |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951376/ https://www.ncbi.nlm.nih.gov/pubmed/20949074 http://dx.doi.org/10.1371/journal.ppat.1001136 |
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