Calcineurin Inhibition at the Clinical Phase of Prion Disease Reduces Neurodegeneration, Improves Behavioral Alterations and Increases Animal Survival

Prion diseases are fatal neurodegenerative disorders characterized by a long pre-symptomatic phase followed by rapid and progressive clinical phase. Although rare in humans, the unconventional infectious nature of the disease raises the potential for an epidemic. Unfortunately, no treatment is curre...

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Detalles Bibliográficos
Autores principales: Mukherjee, Abhisek, Morales-Scheihing, Diego, Gonzalez-Romero, Dennisse, Green, Kristi, Taglialatela, Giulio, Soto, Claudio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951383/
https://www.ncbi.nlm.nih.gov/pubmed/20949081
http://dx.doi.org/10.1371/journal.ppat.1001138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951383/
https://www.ncbi.nlm.nih.gov/pubmed/20949081
http://dx.doi.org/10.1371/journal.ppat.1001138

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