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Selection of Potent Non-Toxic Inhibitory Sequences from a Randomized HIV-1 Specific Lentiviral Short Hairpin RNA Library

RNA interference (RNAi) has been considered as an efficient therapeutic approach against the human immunodeficiency virus type 1 (HIV-1). However, to establish a durable inhibition of HIV-1, multiple effective short hairpin RNAs (shRNAs) need to be stably expressed to prevent the emergence of viral...

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Detalles Bibliográficos
Autores principales:	Pongratz, Carola, Yazdanpanah, Benjamin, Kashkar, Hamid, Lehmann, Maik J., Kräusslich, Hans-Georg, Krönke, Martin
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951894/ https://www.ncbi.nlm.nih.gov/pubmed/20949027 http://dx.doi.org/10.1371/journal.pone.0013172

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