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Potential redox-sensitive Akt activation by dopamine activates Bad and promotes cell death in melanocytes
Dopamine (DA) is a well known oxidative neurotoxin. In addition, Akt has been reported to deliver a survival signal that inhibits apoptosis. However, it has also been reported that chronic Akt activation leads to apoptosis in response to oxidative stress. The objective of the present study was to in...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952081/ https://www.ncbi.nlm.nih.gov/pubmed/20716947 http://dx.doi.org/10.4161/oxim.3.3.8 |