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Gene–environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis

BACKGROUND: Previous studies have reported an interaction between ever cigarette smoking and the presence of the human leukocyte antigen (HLA)-DRB1 shared epitope (SE) genotype and rheumatoid arthritis (RA) risk. To address the effect of dosage, a case-control study nested within two prospective coh...

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Detalles Bibliográficos
Autores principales:	Karlson, E W, Chang, S-C, Cui, J, Chibnik, L B, Fraser, P A, De Vivo, I, Costenbader, K H
Formato:	Texto
Lenguaje:	English
Publicado:	BMJ Group 2009
Materias:	Clinical and Epidemiological Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952498/ https://www.ncbi.nlm.nih.gov/pubmed/19151010 http://dx.doi.org/10.1136/ard.2008.102962

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