Discovery of a Novel and Rich Source of Gluten-Degrading Microbial Enzymes in the Oral Cavity

BACKGROUND: Celiac disease is a T cell mediated-inflammatory enteropathy caused by the ingestion of gluten in genetically predisposed individuals carrying HLA-DQ2 or HLA-DQ8. The immunogenic gliadin epitopes, containing multiple glutamine and proline residues, are largely resistant to degradation by...

Descripción completa

Detalles Bibliográficos
Autores principales: Helmerhorst, Eva J., Zamakhchari, Maram, Schuppan, Detlef, Oppenheim, Frank G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952584/
https://www.ncbi.nlm.nih.gov/pubmed/20948997
http://dx.doi.org/10.1371/journal.pone.0013264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952584/
https://www.ncbi.nlm.nih.gov/pubmed/20948997
http://dx.doi.org/10.1371/journal.pone.0013264

Ejemplares similares