Gene Expression Profiling of U12-Type Spliceosome Mutant Drosophila Reveals Widespread Changes in Metabolic Pathways

BACKGROUND: The U12-type spliceosome is responsible for the removal of a subset of introns from eukaryotic mRNAs. U12-type introns are spliced less efficiently than normal U2-type introns, which suggests a rate-limiting role in gene expression. The Drosophila genome contains about 20 U12-type intron...

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Detalles Bibliográficos
Autores principales: Pessa, Heli K. J., Greco, Dario, Kvist, Jouni, Wahlström, Gudrun, Heino, Tapio I., Auvinen, Petri, Frilander, Mikko J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952598/
https://www.ncbi.nlm.nih.gov/pubmed/20949011
http://dx.doi.org/10.1371/journal.pone.0013215

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