Cargando…
Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
PURPOSE: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine. METHODS: A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due t...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952618/ https://www.ncbi.nlm.nih.gov/pubmed/20957062 http://dx.doi.org/10.2147/OPTH.S13831 |
_version_ | 1782187792960323584 |
---|---|
author | Kuennen, Rebecca A Smith, Reynell Harder Mauger, Thomas F Craig, Elson |
author_facet | Kuennen, Rebecca A Smith, Reynell Harder Mauger, Thomas F Craig, Elson |
author_sort | Kuennen, Rebecca A |
collection | PubMed |
description | PURPOSE: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine. METHODS: A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due to incapacitating pain. RESULTS: The eye showed Acanthamoeba organisms within the cornea and evidence of acute and chronic inflammation throughout the remainder of the eye. The patient has survived without orbital recurrence for 2 years. CONCLUSIONS: This case demonstrates late inflammation with active Acanthameoba keratitis following systemic pentamidine therapy. |
format | Text |
id | pubmed-2952618 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-29526182010-10-18 Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis Kuennen, Rebecca A Smith, Reynell Harder Mauger, Thomas F Craig, Elson Clin Ophthalmol Case Report PURPOSE: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine. METHODS: A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due to incapacitating pain. RESULTS: The eye showed Acanthamoeba organisms within the cornea and evidence of acute and chronic inflammation throughout the remainder of the eye. The patient has survived without orbital recurrence for 2 years. CONCLUSIONS: This case demonstrates late inflammation with active Acanthameoba keratitis following systemic pentamidine therapy. Dove Medical Press 2010-10-05 2010 /pmc/articles/PMC2952618/ /pubmed/20957062 http://dx.doi.org/10.2147/OPTH.S13831 Text en © 2010 Kuennen et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Case Report Kuennen, Rebecca A Smith, Reynell Harder Mauger, Thomas F Craig, Elson Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis |
title | Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis |
title_full | Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis |
title_fullStr | Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis |
title_full_unstemmed | Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis |
title_short | Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis |
title_sort | enucleation following treatment with intravenous pentamidine for acanthamoeba sclerokeratitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952618/ https://www.ncbi.nlm.nih.gov/pubmed/20957062 http://dx.doi.org/10.2147/OPTH.S13831 |
work_keys_str_mv | AT kuennenrebeccaa enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis AT smithreynellharder enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis AT maugerthomasf enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis AT craigelson enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis |