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Inhibition of the Nuclear Factor-κB Pathway Prevents Beta Cell Failure and Diet Induced Diabetes in Psammomys obesus
BACKGROUND: High doses of anti-inflammatory drugs, such as aspirin and salicylates, improve glucose metabolism in insulin resistant and type 2 diabetic patients. It has also been shown that the glucose lowering effect is related to the unspecific ability of these drugs to inhibit inhibitor kinaseβ (...
Autores principales: | Friberg, Josefine, Tonnesen, Morten F., Heller, Schott, Pociot, Flemming, Bödvarsdottir, Thóra B., Karlsen, Allan E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952629/ https://www.ncbi.nlm.nih.gov/pubmed/20948968 http://dx.doi.org/10.1371/journal.pone.0013341 |
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