Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys

Despite the eradication of smallpox, there is heightened concern that it could be reintroduced as a result of intentional release of Variola major virus through an act of bioterrorism. The live vaccine that was pivotal in the eradication of smallpox though considered a gold standard for its efficacy...

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Detalles Bibliográficos
Autores principales: Zielinski, Rafal J., Smedley, Jeremy V., Perera, Pin-Yu, Silvera, Peter M., Waldmann, Thomas A., Capala, Jacek, Perera, Liyanage P.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952667/
https://www.ncbi.nlm.nih.gov/pubmed/20728526
http://dx.doi.org/10.1016/j.vaccine.2010.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952667/
https://www.ncbi.nlm.nih.gov/pubmed/20728526
http://dx.doi.org/10.1016/j.vaccine.2010.08.008

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