Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report

Polyostotic fibrous dysplasia (FD) associated to McCune-Albright Syndrome (MAS) often leads to fractures, deformities, and bone pain resulting in bad quality of life. Parenteral bisphosphonates have been used in children and adolescents to improve these symptoms with few adverse effects. We evaluate...

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Detalles Bibliográficos
Autores principales: Aragão, Ana Luiza Andrade, Silva, Ivani Novato
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952807/
https://www.ncbi.nlm.nih.gov/pubmed/20976302
http://dx.doi.org/10.1155/2010/432060
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author Aragão, Ana Luiza Andrade
Silva, Ivani Novato
author_facet Aragão, Ana Luiza Andrade
Silva, Ivani Novato
author_sort Aragão, Ana Luiza Andrade
collection PubMed
description Polyostotic fibrous dysplasia (FD) associated to McCune-Albright Syndrome (MAS) often leads to fractures, deformities, and bone pain resulting in bad quality of life. Parenteral bisphosphonates have been used in children and adolescents to improve these symptoms with few adverse effects. We evaluated the response to oral Alendronate in a girl with severe MAS FD and observed improved quality of life with reduction of bone pain.
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spelling pubmed-29528072010-10-25 Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report Aragão, Ana Luiza Andrade Silva, Ivani Novato Int J Pediatr Endocrinol Case Report Polyostotic fibrous dysplasia (FD) associated to McCune-Albright Syndrome (MAS) often leads to fractures, deformities, and bone pain resulting in bad quality of life. Parenteral bisphosphonates have been used in children and adolescents to improve these symptoms with few adverse effects. We evaluated the response to oral Alendronate in a girl with severe MAS FD and observed improved quality of life with reduction of bone pain. BioMed Central 2010 2010-09-21 /pmc/articles/PMC2952807/ /pubmed/20976302 http://dx.doi.org/10.1155/2010/432060 Text en Copyright © 2010 Aragão and Silva. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aragão, Ana Luiza Andrade
Silva, Ivani Novato
Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report
title Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report
title_full Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report
title_fullStr Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report
title_full_unstemmed Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report
title_short Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report
title_sort oral alendronate treatment for severe polyostotic fibrous dysplasia due to mccune-albright syndrome in a child: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952807/
https://www.ncbi.nlm.nih.gov/pubmed/20976302
http://dx.doi.org/10.1155/2010/432060
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AT silvaivaninovato oralalendronatetreatmentforseverepolyostoticfibrousdysplasiaduetomccunealbrightsyndromeinachildacasereport

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