Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls

Smoke constituents can induce DNA adducts that cause mutations and lead to lung cancer. We have analyzed DNA adducts and polymorphisms in two DNA repair genes, for example, XRCC1 Arg194Trp and Arg399Gln genes and XRCC3 Thr241Met gene, in 34 lung cancer cases in respect to 30 subjects with benign lun...

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Detalles Bibliográficos
Autores principales: Peluso, Marco, Munnia, Armelle, Piro, Sara, Armillis, Alessandra, Ceppi, Marcello, Matullo, Giuseppe, Puntoni, Riccardo
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952824/
https://www.ncbi.nlm.nih.gov/pubmed/20976253
http://dx.doi.org/10.4061/2010/386798

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