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Protein evolution in yeast transcription factor subnetworks
When averaged over the full yeast protein–protein interaction and transcriptional regulatory networks, protein hubs with many interaction partners or regulators tend to evolve significantly more slowly due to increased negative selection. However, genome-wide analysis of protein evolution in the sub...
Autores principales: | Wang, Yong, Franzosa, Eric A., Zhang, Xiang-Sun, Xia, Yu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952844/ https://www.ncbi.nlm.nih.gov/pubmed/20466810 http://dx.doi.org/10.1093/nar/gkq353 |
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