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Structural signatures of antibiotic binding sites on the ribosome
The ribosome represents a major target for antibacterial drugs. Being a complex molecular machine, it offers many potential sites for functional interference. The high-resolution structures of ribosome in complex with various antibiotics provide a unique data set for understanding the universal feat...
Autores principales: | David-Eden, Hilda, Mankin, Alexander S., Mandel-Gutfreund, Yael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952860/ https://www.ncbi.nlm.nih.gov/pubmed/20494981 http://dx.doi.org/10.1093/nar/gkq411 |
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