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Molecular dynamics simulations suggest that RNA three-way junctions can act as flexible RNA structural elements in the ribosome

We present extensive explicit solvent molecular dynamics analysis of three RNA three-way junctions (3WJs) from the large ribosomal subunit: the 3WJ formed by Helices 90–92 (H90–H92) of 23S rRNA; the 3WJ formed by H42–H44 organizing the GTPase associated center (GAC) of 23S rRNA; and the 3WJ of 5S rR...

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Detalles Bibliográficos
Autores principales: Beššeová, Ivana, Réblová, Kamila, Leontis, Neocles B., Šponer, Jiří
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952862/
https://www.ncbi.nlm.nih.gov/pubmed/20507916
http://dx.doi.org/10.1093/nar/gkq414