Muscle Atrophy and Motor Neuron Degeneration in Human NEDL1 Transgenic Mice

Amyotrophic lateral sclerosis (ALS) is the most frequent adult-onset motor neuron disease. Approximately 20% cases of familial ALS show the mutation in the superoxide dismutase-1 (SOD1) gene. We previously demonstrated that homologue to E6AP carboxyl terminus- (HECT-) type ubiquitin protein E3 ligas...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Haraguchi, Seiki, Koda, Tadayuki, Hashimoto, Kenji, Nakagawara, Akira
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952905/
https://www.ncbi.nlm.nih.gov/pubmed/20976258
http://dx.doi.org/10.1155/2011/831092

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