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Angiogenesis and Breast Cancer
Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952923/ https://www.ncbi.nlm.nih.gov/pubmed/20953378 http://dx.doi.org/10.1155/2010/576384 |
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author | Longatto Filho, Adhemar Lopes, José Manuel Schmitt, Fernando C. |
author_facet | Longatto Filho, Adhemar Lopes, José Manuel Schmitt, Fernando C. |
author_sort | Longatto Filho, Adhemar |
collection | PubMed |
description | Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways regulating angiogenesis is constantly growing. An increased and complex scenario of angiogenesis is nowadays available in breast cancer, specifically, and permits not only to understand most of the important phases of neoplastic growth but also offer an exciting perspective for new therapeutic proposals based on blocking new blood vessels sprouting. This review focused on historical and recent understanding of angiogenesis occurrence in breast cancer. |
format | Text |
id | pubmed-2952923 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-29529232010-10-15 Angiogenesis and Breast Cancer Longatto Filho, Adhemar Lopes, José Manuel Schmitt, Fernando C. J Oncol Review Article Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways regulating angiogenesis is constantly growing. An increased and complex scenario of angiogenesis is nowadays available in breast cancer, specifically, and permits not only to understand most of the important phases of neoplastic growth but also offer an exciting perspective for new therapeutic proposals based on blocking new blood vessels sprouting. This review focused on historical and recent understanding of angiogenesis occurrence in breast cancer. Hindawi Publishing Corporation 2010 2010-10-07 /pmc/articles/PMC2952923/ /pubmed/20953378 http://dx.doi.org/10.1155/2010/576384 Text en Copyright © 2010 Adhemar Longatto Filho et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Longatto Filho, Adhemar Lopes, José Manuel Schmitt, Fernando C. Angiogenesis and Breast Cancer |
title | Angiogenesis and Breast Cancer |
title_full | Angiogenesis and Breast Cancer |
title_fullStr | Angiogenesis and Breast Cancer |
title_full_unstemmed | Angiogenesis and Breast Cancer |
title_short | Angiogenesis and Breast Cancer |
title_sort | angiogenesis and breast cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952923/ https://www.ncbi.nlm.nih.gov/pubmed/20953378 http://dx.doi.org/10.1155/2010/576384 |
work_keys_str_mv | AT longattofilhoadhemar angiogenesisandbreastcancer AT lopesjosemanuel angiogenesisandbreastcancer AT schmittfernandoc angiogenesisandbreastcancer |