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Angiogenesis and Breast Cancer

Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways...

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Detalles Bibliográficos
Autores principales: Longatto Filho, Adhemar, Lopes, José Manuel, Schmitt, Fernando C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952923/
https://www.ncbi.nlm.nih.gov/pubmed/20953378
http://dx.doi.org/10.1155/2010/576384
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author Longatto Filho, Adhemar
Lopes, José Manuel
Schmitt, Fernando C.
author_facet Longatto Filho, Adhemar
Lopes, José Manuel
Schmitt, Fernando C.
author_sort Longatto Filho, Adhemar
collection PubMed
description Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways regulating angiogenesis is constantly growing. An increased and complex scenario of angiogenesis is nowadays available in breast cancer, specifically, and permits not only to understand most of the important phases of neoplastic growth but also offer an exciting perspective for new therapeutic proposals based on blocking new blood vessels sprouting. This review focused on historical and recent understanding of angiogenesis occurrence in breast cancer.
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spelling pubmed-29529232010-10-15 Angiogenesis and Breast Cancer Longatto Filho, Adhemar Lopes, José Manuel Schmitt, Fernando C. J Oncol Review Article Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways regulating angiogenesis is constantly growing. An increased and complex scenario of angiogenesis is nowadays available in breast cancer, specifically, and permits not only to understand most of the important phases of neoplastic growth but also offer an exciting perspective for new therapeutic proposals based on blocking new blood vessels sprouting. This review focused on historical and recent understanding of angiogenesis occurrence in breast cancer. Hindawi Publishing Corporation 2010 2010-10-07 /pmc/articles/PMC2952923/ /pubmed/20953378 http://dx.doi.org/10.1155/2010/576384 Text en Copyright © 2010 Adhemar Longatto Filho et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Longatto Filho, Adhemar
Lopes, José Manuel
Schmitt, Fernando C.
Angiogenesis and Breast Cancer
title Angiogenesis and Breast Cancer
title_full Angiogenesis and Breast Cancer
title_fullStr Angiogenesis and Breast Cancer
title_full_unstemmed Angiogenesis and Breast Cancer
title_short Angiogenesis and Breast Cancer
title_sort angiogenesis and breast cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952923/
https://www.ncbi.nlm.nih.gov/pubmed/20953378
http://dx.doi.org/10.1155/2010/576384
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