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miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells

MicroRNAs (miRNAs) are a class of small non-coding RNAs (ncRNAs) that regulate gene expression by repressing translation or triggering the degradation of complementary mRNA sequences. Certain miRNAs have been shown to function as integral components of the p53 and/or retinoblastoma (Rb) regulatory n...

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Detalles Bibliográficos
Autores principales: Noonan, Emily J., Place, Robert F., Basak, Shashwati, Pookot, Deepa, Li, Long-Cheng
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952964/
https://www.ncbi.nlm.nih.gov/pubmed/20948989

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