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Induction of Toll-Like Receptor 3-Mediated Immunity during Gestation Inhibits Cortical Neurogenesis and Causes Behavioral Disturbances

Maternal infection during pregnancy with a wide range of RNA and DNA viruses is associated with increased risk for schizophrenia and autism in their offspring. A common feature in these exposures is that virus replication induces innate immunity through interaction with Toll-like receptors (TLRs). W...

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Detalles Bibliográficos
Autores principales: De Miranda, Joari, Yaddanapudi, Kavitha, Hornig, Mady, Villar, Gabriel, Serge, Robert, Lipkin, W. Ian
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953007/
https://www.ncbi.nlm.nih.gov/pubmed/20941330
http://dx.doi.org/10.1128/mBio.00176-10