Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice

Rosiglitazone (RSG), developed for the treatment of type 2 diabetes mellitus, is known to have potent effects on carbohydrate and lipid metabolism leading to the improvement of insulin sensitivity in target tissues. To further assess the capacity of RSG to normalize gene expression in insulin-sensit...

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Detalles Bibliográficos
Autores principales: Le Bouter, Sabrina, Rodriguez, Marianne, Guigal-Stephan, Nolwen, Courtade-Gaïani, Sophie, Xuereb, Laura, de Montrion, Catherine, Croixmarie, Vincent, Umbdenstock, Thierry, Boursier-Neyret, Claire, Lonchampt, Michel, Brun, Manuel, Dacquet, Catherine, Ktorza, Alain, Lockhart, Brian-Paul, Galizzi, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953354/
https://www.ncbi.nlm.nih.gov/pubmed/20953342
http://dx.doi.org/10.1155/2010/679184

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