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BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

Polycomb group (PcG) proteins are major determinants of cell identity, stem cell pluripotency, and epigenetic gene silencing during development. The polycomb repressive complex 1, which contains BMI1, RING1, and RING2, functions as an E3-ubuiquitin ligase. We found that BMI1 and RING2 are recruited...

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Detalles Bibliográficos
Autores principales:	Ismail, Ismail Hassan, Andrin, Christi, McDonald, Darin, Hendzel, Michael J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953429/ https://www.ncbi.nlm.nih.gov/pubmed/20921134 http://dx.doi.org/10.1083/jcb.201003034

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