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JunB transcription factor maintains skeletal muscle mass and promotes hypertrophy
The size of skeletal muscle cells is precisely regulated by intracellular signaling networks that determine the balance between overall rates of protein synthesis and degradation. Myofiber growth and protein synthesis are stimulated by the IGF-1/Akt/mammalian target of rapamycin (mTOR) pathway. In t...
Autores principales: | Raffaello, Anna, Milan, Giulia, Masiero, Eva, Carnio, Silvia, Lee, Donghoon, Lanfranchi, Gerolamo, Goldberg, Alfred Lewis, Sandri, Marco |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953439/ https://www.ncbi.nlm.nih.gov/pubmed/20921137 http://dx.doi.org/10.1083/jcb.201001136 |
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