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T Regulatory Cells in Cord Blood—FOXP3 Demethylation as Reliable Quantitative Marker

BACKGROUND: Regulatory T-cells (Tregs), characterized as CD4+CD25(hi) T-cells expressing FOXP3, play a crucial role in controlling healthy immune development during early immune maturation. Recently, FOXP3 demethylation was suggested to be a novel marker for natural Tregs in adults. In cord blood, t...

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Detalles Bibliográficos
Autores principales:	Liu, Jing, Lluis, Anna, Illi, Sabina, Layland, Laura, Olek, Sven, von Mutius, Erika, Schaub, Bianca
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953505/ https://www.ncbi.nlm.nih.gov/pubmed/20967272 http://dx.doi.org/10.1371/journal.pone.0013267

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