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Yokukansan Inhibits Neuronal Death during ER Stress by Regulating the Unfolded Protein Response

BACKGROUND: Recently, several studies have reported Yokukansan (Tsumura TJ-54), a traditional Japanese medicine, as a potential new drug for the treatment of Alzheimer's disease (AD). Endoplasmic reticulum (ER) stress is known to play an important role in the pathogenesis of AD, particularly in...

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Detalles Bibliográficos
Autores principales: Hiratsuka, Toru, Matsuzaki, Shinsuke, Miyata, Shingo, Kinoshita, Mitsuhiro, Kakehi, Kazuaki, Nishida, Shinji, Katayama, Taiichi, Tohyama, Masaya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953506/
https://www.ncbi.nlm.nih.gov/pubmed/20967273
http://dx.doi.org/10.1371/journal.pone.0013280