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Tissue Transglutaminase Promotes Drug Resistance and Invasion by Inducing Mesenchymal Transition in Mammary Epithelial Cells

Recent observations that aberrant expression of tissue transglutaminase (TG2) promotes growth, survival, and metastasis of multiple tumor types is of great significance and could yield novel therapeutic targets for improved patient outcomes. To accomplish this, a clear understanding of how TG2 contr...

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Detalles Bibliográficos
Autores principales: Kumar, Anupam, Xu, Jia, Brady, Samuel, Gao, Hui, Yu, Dihua, Reuben, James, Mehta, Kapil
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953521/
https://www.ncbi.nlm.nih.gov/pubmed/20967228
http://dx.doi.org/10.1371/journal.pone.0013390