Cargando…
Tissue Transglutaminase Promotes Drug Resistance and Invasion by Inducing Mesenchymal Transition in Mammary Epithelial Cells
Recent observations that aberrant expression of tissue transglutaminase (TG2) promotes growth, survival, and metastasis of multiple tumor types is of great significance and could yield novel therapeutic targets for improved patient outcomes. To accomplish this, a clear understanding of how TG2 contr...
Autores principales: | Kumar, Anupam, Xu, Jia, Brady, Samuel, Gao, Hui, Yu, Dihua, Reuben, James, Mehta, Kapil |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953521/ https://www.ncbi.nlm.nih.gov/pubmed/20967228 http://dx.doi.org/10.1371/journal.pone.0013390 |
Ejemplares similares
-
Evidence That Aberrant Expression of Tissue Transglutaminase Promotes Stem Cell Characteristics in Mammary Epithelial Cells
por: Kumar, Anupam, et al.
Publicado: (2011) -
Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells
por: Kumar, Anupam, et al.
Publicado: (2012) -
Epithelial to mesenchymal transition in mammary gland tissue fibrosis and insights into drug therapeutics
por: Syed, Mudasir Ahmad, et al.
Publicado: (2023) -
Tissue transglutaminase-induced alterations in extracellular matrix inhibit tumor invasion
por: Mangala, Lingegowda S, et al.
Publicado: (2005) -
Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cells
por: Ayinde, Oluseyi, et al.
Publicado: (2017)