Single-Dose Mucosal Immunization with a Candidate Universal Influenza Vaccine Provides Rapid Protection from Virulent H5N1, H3N2 and H1N1 Viruses

BACKGROUND: The sudden emergence of novel influenza viruses is a global public health concern. Conventional influenza vaccines targeting the highly variable surface glycoproteins hemagglutinin and neuraminidase must antigenically match the emerging strain to be effective. In contrast, “universal” va...

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Detalles Bibliográficos
Autores principales: Price, Graeme E., Soboleski, Mark R., Lo, Chia-Yun, Misplon, Julia A., Quirion, Mary R., Houser, Katherine V., Pearce, Melissa B., Pappas, Claudia, Tumpey, Terrence M., Epstein, Suzanne L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953831/
https://www.ncbi.nlm.nih.gov/pubmed/20976273
http://dx.doi.org/10.1371/journal.pone.0013162

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