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Production and Characterisation of a Neutralising Chimeric Antibody against Botulinum Neurotoxin A

Botulinum neurotoxins, produced by Clostridium botulinum bacteria, are the causative agent of botulism. This disease only affects a few hundred people each year, thus ranking it among the orphan diseases. However, botulinum toxin type A (BoNT/A) is the most potent toxin known to man. Due to their po...

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Detalles Bibliográficos
Autores principales: Prigent, Julie, Mazuet, Christelle, Boquet, Didier, Lamourette, Patricia, Volland, Hervé, Popoff, Michel R., Créminon, Christophe, Simon, Stéphanie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953832/
https://www.ncbi.nlm.nih.gov/pubmed/20967241
http://dx.doi.org/10.1371/journal.pone.0013245