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Transmission of Hemagglutinin D222G Mutant Strain of Pandemic (H1N1) 2009 Virus

A pandemic (H1N1) 2009 virus strain carrying the D222G mutation was identified in a severely ill man and was transmitted to a household contact. Only mild illness developed in the contact, despite his obesity and diabetes. The isolated virus reacted fully with an antiserum against the pandemic vacci...

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Detalles Bibliográficos
Autores principales: Puzelli, Simona, Facchini, Marzia, Spagnolo, Domenico, De Marco, Maria A., Calzoletti, Laura, Zanetti, Alessandro, Fumagalli, Roberto, Tanzi, Maria L., Cassone, Antonio, Rezza, Giovanni, Donatelli, Isabella
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954012/
https://www.ncbi.nlm.nih.gov/pubmed/20409386
http://dx.doi.org/10.3201/eid1605.091858
Descripción
Sumario:A pandemic (H1N1) 2009 virus strain carrying the D222G mutation was identified in a severely ill man and was transmitted to a household contact. Only mild illness developed in the contact, despite his obesity and diabetes. The isolated virus reacted fully with an antiserum against the pandemic vaccine strain.