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P66SHC and Ageing: ROS and TOR?
Both Reactive Oxygen Species (ROS) and hyperactivation of the nutrient-sensing mTOR/S6 kinase cascade have been linked to aging and age-related diseases as well as to the anti-aging effect of calorie restriction. Recent findings that the pro-aging and pro-oxidant molecule p66shc contributes to S6K a...
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| Formato: | Texto |
| Lenguaje: | English |
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Impact Journals LLC
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954042/ https://www.ncbi.nlm.nih.gov/pubmed/20689155 |