Arp2/3- and Cofilin-coordinated Actin Dynamics Is Required for Insulin-mediated GLUT4 Translocation to the Surface of Muscle Cells

GLUT4 vesicles are actively recruited to the muscle cell surface upon insulin stimulation. Key to this process is Rac-dependent reorganization of filamentous actin beneath the plasma membrane, but the underlying molecular mechanisms have yet to be elucidated. Using L6 rat skeletal myoblasts stably e...

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Detalles Bibliográficos
Autores principales: Chiu, Tim Ting, Patel, Nish, Shaw, Alisa E., Bamburg, James R., Klip, Amira
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954118/
https://www.ncbi.nlm.nih.gov/pubmed/20739464
http://dx.doi.org/10.1091/mbc.E10-04-0316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954118/
https://www.ncbi.nlm.nih.gov/pubmed/20739464
http://dx.doi.org/10.1091/mbc.E10-04-0316

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