Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2

Mitochondrial respiratory stress (also called mitochondrial retrograde signaling) activates a Ca(2+)/calcineurin-mediated signal that culminates in transcription activation/repression of a large number of nuclear genes. This signal is propagated through activation of the regulatory proteins NFκB c-R...

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Detalles Bibliográficos
Autores principales: Guha, Manti, Fang, Ji-Kang, Monks, Robert, Birnbaum, Morris J., Avadhani, Narayan G.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954122/
https://www.ncbi.nlm.nih.gov/pubmed/20719961
http://dx.doi.org/10.1091/mbc.E10-03-0192

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