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Phosphorylation of p27(Kip1) at Thr187 by Cyclin-dependent Kinase 5 Modulates Neural Stem Cell Differentiation
Cyclin-dependent kinase 5 (Cdk5) plays a key role in the development of the mammalian nervous system; it phosphorylates a number of targeted proteins involved in neuronal migration during development to synaptic activity in the mature nervous system. Its role in the initial stages of neuronal commit...
Autores principales: | Zheng, Ya-Li, Li, Bing-Sheng, Rudrabhatla, Parvathi, Shukla, Varsha, Amin, Niranjana D., Maric, Dragan, Kesavapany, Sashi, Kanungo, Jyotshnabala, Pareek, Tej K., Takahashi, Satoru, Grant, Philip, Kulkarni, Ashok B., Pant, Harish C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954124/ https://www.ncbi.nlm.nih.gov/pubmed/20810788 http://dx.doi.org/10.1091/mbc.E10-01-0054 |
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