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Cytochrome P450 Reductase: A Harbinger of Diffusible Reduced Oxygen Species
The bi-enzymatic system of cytochrome P450 (CYP, a hemoprotein) and cytochrome P450 reductase (CPR, a diflavoenzyme) mediate the redox metabolism of diverse indigenous and xenobiotic molecules in various cellular and organ systems, using oxygen and NADPH. Curiously, when a 1∶1 ratio is seen to be op...
Autores principales: | Manoj, Kelath Murali, Gade, Sudeep Kumar, Mathew, Lazar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954143/ https://www.ncbi.nlm.nih.gov/pubmed/20967245 http://dx.doi.org/10.1371/journal.pone.0013272 |
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