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Cytochrome P450 Reductase: A Harbinger of Diffusible Reduced Oxygen Species

The bi-enzymatic system of cytochrome P450 (CYP, a hemoprotein) and cytochrome P450 reductase (CPR, a diflavoenzyme) mediate the redox metabolism of diverse indigenous and xenobiotic molecules in various cellular and organ systems, using oxygen and NADPH. Curiously, when a 1∶1 ratio is seen to be op...

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Detalles Bibliográficos
Autores principales: Manoj, Kelath Murali, Gade, Sudeep Kumar, Mathew, Lazar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954143/
https://www.ncbi.nlm.nih.gov/pubmed/20967245
http://dx.doi.org/10.1371/journal.pone.0013272

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