Multiple Routes and Milestones in the Folding of HIV–1 Protease Monomer

Proteins fold on a time scale incompatible with a mechanism of random search in conformational space thus indicating that somehow they are guided to the native state through a funneled energetic landscape. At the same time the heterogeneous kinetics suggests the existence of several different foldin...

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Detalles Bibliográficos
Autores principales: Bonomi, Massimiliano, Barducci, Alessandro, Gervasio, Francesco L., Parrinello, Michele
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954147/
https://www.ncbi.nlm.nih.gov/pubmed/20967249
http://dx.doi.org/10.1371/journal.pone.0013208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954147/
https://www.ncbi.nlm.nih.gov/pubmed/20967249
http://dx.doi.org/10.1371/journal.pone.0013208

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