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Anthrax Lethal Toxin Suppresses Murine Cardiomyocyte Contractile Function and Intracellular Ca(2+) Handling via a NADPH Oxidase-Dependent Mechanism
OBJECTIVES: Anthrax infection is associated with devastating cardiovascular sequelae, suggesting unfavorable cardiovascular effects of toxins originated from Bacillus anthracis namely lethal and edema toxins. This study was designed to examine the direct effect of lethal toxins on cardiomyocyte cont...
Autores principales: | Kandadi, Machender R., Hua, Yinan, Ma, Heng, Li, Qun, Kuo, Shu-ru, Frankel, Arthur E., Ren, Jun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954163/ https://www.ncbi.nlm.nih.gov/pubmed/20967205 http://dx.doi.org/10.1371/journal.pone.0013335 |
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