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New variants of known folds: do they bring new biology?

New distinct versions of known protein folds provide a powerful means of protein-function prediction that complements sequence and genomic context analysis. These structures do not supplant direct biochemical experiments, but are indispensable for the complete characterization of proteins.

Detalles Bibliográficos
Autor principal: Koonin, Eugene V.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954209/
https://www.ncbi.nlm.nih.gov/pubmed/20944215
http://dx.doi.org/10.1107/S1744309110013242
Descripción
Sumario:New distinct versions of known protein folds provide a powerful means of protein-function prediction that complements sequence and genomic context analysis. These structures do not supplant direct biochemical experiments, but are indispensable for the complete characterization of proteins.