A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution

BT1062 from Bacteroides thetaiotaomicron is a homolog of Mfa2 (PGN0288 or PG0179), which is a component of the minor fimbriae in Porphyromonas gingivalis. The crystal structure of BT1062 revealed a conserved fold that is widely adopted by fimbrial components.

Detalles Bibliográficos
Autores principales: Xu, Qingping, Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Bakolitsa, Constantina, Cai, Xiaohui, Carlton, Dennis, Chen, Connie, Chiu, Hsiu-Ju, Chiu, Michelle, Clayton, Thomas, Das, Debanu, Deller, Marc C., Duan, Lian, Ellrott, Kyle, Farr, Carol L., Feuerhelm, Julie, Grant, Joanna C., Grzechnik, Anna, Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Krishna, S. Sri, Kumar, Abhinav, Marciano, David, McMullan, Daniel, Miller, Mitchell D., Morse, Andrew T., Nigoghossian, Edward, Nopakun, Amanda, Okach, Linda, Puckett, Christina, Reyes, Ron, Sefcovic, Natasha, Tien, Henry J., Trame, Christine B., van den Bedem, Henry, Weekes, Dana, Wooten, Tiffany, Yeh, Andrew, Zhou, Jiadong, Hodgson, Keith O., Wooley, John, Elsliger, Marc-Andre, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Human Gut Microbiome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954217/
https://www.ncbi.nlm.nih.gov/pubmed/20944223
http://dx.doi.org/10.1107/S1744309110006548
Descripción
Sumario:BT1062 from Bacteroides thetaiotaomicron is a homolog of Mfa2 (PGN0288 or PG0179), which is a component of the minor fimbriae in Porphyromonas gingivalis. The crystal structure of BT1062 revealed a conserved fold that is widely adopted by fimbrial components.

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