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Ligands in crystal structures that aid in functional characterization

Liganded structures can be instrumental in assigning function to uncharacterized proteins by revealing active sites, conserved residues, binding motifs, and substrate specificity. This introduction provides an overview and commentary on the value of liganded structures emerging from the JCSG structu...

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Detalles Bibliográficos
Autores principales: Speers, Anna E., Cravatt, Benjamin F.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954220/
https://www.ncbi.nlm.nih.gov/pubmed/20944226
http://dx.doi.org/10.1107/S1744309110035748

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