Two Functionally Distinct Isoforms of TL1A (TNFSF15) Generated by Differential Ectodomain Shedding

Tumor necrosis factor–like cytokine 1A (TL1A) is expressed in endothelial cells and contributes to T-cell activation, via an extracellular fragment TL1A(L72-L251), generated by ectodomain shedding. Fragments of TL1A, referred to as vascular endothelial growth inhibitor, were found to induce growth a...

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Detalles Bibliográficos
Autores principales: Mück, Christoph, Herndler-Brandstetter, Dietmar, Micutkova, Lucia, Grubeck-Loebenstein, Beatrix, Jansen-Dürr, Pidder
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Journal of Gerontology: BIOLOGICAL SCIENCES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954241/
https://www.ncbi.nlm.nih.gov/pubmed/20675618
http://dx.doi.org/10.1093/gerona/glq129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954241/
https://www.ncbi.nlm.nih.gov/pubmed/20675618
http://dx.doi.org/10.1093/gerona/glq129

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