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Two Functionally Distinct Isoforms of TL1A (TNFSF15) Generated by Differential Ectodomain Shedding
Tumor necrosis factor–like cytokine 1A (TL1A) is expressed in endothelial cells and contributes to T-cell activation, via an extracellular fragment TL1A(L72-L251), generated by ectodomain shedding. Fragments of TL1A, referred to as vascular endothelial growth inhibitor, were found to induce growth a...
Autores principales: | Mück, Christoph, Herndler-Brandstetter, Dietmar, Micutkova, Lucia, Grubeck-Loebenstein, Beatrix, Jansen-Dürr, Pidder |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954241/ https://www.ncbi.nlm.nih.gov/pubmed/20675618 http://dx.doi.org/10.1093/gerona/glq129 |
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