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Recent advances in diagnosis and treatment of atypical haemolytic uraemic syndrome

New understanding of the underlying pathology of the thrombotic microangiopathies has resulted in guidelines for the investigation and management of atypical haemolytic uraemic syndrome in children and adults and the prospect of new therapies, which are in clinical trial. Patients should be investig...

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Detalles Bibliográficos
Autor principal: Bolton-Maggs, Paula HB
Formato: Texto
Lenguaje:English
Publicado: Medicine Reports Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954421/
https://www.ncbi.nlm.nih.gov/pubmed/20948827
http://dx.doi.org/10.3410/M2-73
Descripción
Sumario:New understanding of the underlying pathology of the thrombotic microangiopathies has resulted in guidelines for the investigation and management of atypical haemolytic uraemic syndrome in children and adults and the prospect of new therapies, which are in clinical trial. Patients should be investigated for defects in complement pathways and a trial of plasma exchange is indicated.